WHAT IS YONSA®?

YONSA® (abiraterone acetate) is a prescription medicine that is used with methylprednisolone to treat prostate cancer that has spread to other parts of the body and no longer responds to medical or surgical treatment that lowers testosterone.

It is not known if YONSA® is safe or effective in children.

YONSA® is not for use in women.

Do not take YONSA® if you are pregnant or may become pregnant. YONSA® may harm your unborn baby. Women who are pregnant or may become pregnant should not handle YONSA® tablets without protection, such as gloves.

125FP

HOW AN INNOVATIVE FORMULATION IMPACTS YOUR TREATMENT PLAN

UNDERSTANDING YOUR DIAGNOSIS

As you may have learned when you were diagnosed by your doctor, cancer cells can spread locally to normal tissue; regionally, to nearby lymph nodes, tissues, or organs; and to distant parts of the body. When this happens, it is called metastatic cancer. The process by which cancer cells spread to other parts of the body is called metastasis.

GOING BEYOND THE DIAGNOSIS

Abiraterone acetate is an antiandrogen medication commonly used in the treatment of prostate cancer, usually in combination with a corticosteroid. It is specifically indicated for use in the treatment of metastatic castration-resistant prostate cancer, or mCRPC.

This therapy inhibits the production of androgens like testosterone and dihydrotestosterone in the body, preventing the effects of these hormones in the prostate and where the cancer cells may have spread.

YONSA® is the first and only micronized formulation for the treatment of metastatic castration-resistant prostate cancer (CRPC).

SAFETY PROFILE

YONSA® is not for use in women. Do not take YONSA® if you are pregnant or may become pregnant. YONSA® may harm your unborn baby. Males with partners of reproductive potential should use contraception.

Do not touch YONSA® tablets without protection (such as gloves) if they are broken, crushed, or damaged.

YONSA® may cause serious side effects, including high blood pressure (hypertension), low blood potassium levels (hypokalemia), and fluid retention (edema). Your doctor will monitor you once a month for these conditions. Your doctor also will monitor you for changes in your liver.

In clinical trials, the most common side effects of YONSA® were fatigue, joint swelling or discomfort, edema, hot flush, diarrhea, vomiting, cough, hypertension, dyspnea, urinary tract infection, and contusion.

mCRPC

YONSA® offers another option in mCRPC therapy

YONSA SUPPORT

You have a lot on your mind. That’s why we’ve created YONSA SUPPORT™. Our case managers are experts in prescription benefits and insurance coverage and may be able to help you find the right financial option to fit your needs and eligibility. The benefits of YONSA SUPPORT™ begin as soon as you enroll and include:

  • Personal, one-on-one assistance from a case manager
  • Financial assistance
  • Co-Pay Program*
  • Support in understanding insurance coverage

Co-pay Program (eligible commercially insured patients)

The YONSA SUPPORT Co-pay Card Program helps eligible commercially insured patients access their YONSA® prescriptions.

  • Patients can check eligibility and activate the co-pay card by visiting www.activatethecard.com/7702
  • Eligible commercially insured patients may pay as little as $10 for each fill of a YONSA® prescription, subject to a maximum program benefit per fill
  • Maximum benefit of up to $12,000 per calendar year*

Patient Assistance Program (PAP)

Patients who are underinsured or uninsured may be eligible to receive free medication. To get your patients started with the Patient Assistance Program, simply complete the YONSA SUPPORT Patient Assistance Program Application, which is available at www.YonsaRx.com.

*Subject to terms and conditions. Must be enrolled in YONSA SUPPORT™ to qualify.

$5,000 maximum program benefit per fill and $12,000 maximum program benefit per calendar year. Not valid for patients without commercial insurance coverage or if prescription is paid for by any state or federally funded healthcare program, including but not limited to Medicare, Medicaid, VA, DOD, or TRICARE. Available to US, Guam, Virgin Islands, or Puerto Rico residents only. See Full Terms and Conditions below.

Income documentation is required. See Program Summary.

HOW TO ENROLL

Simply fill in the patient enrollment form available for download here.

If you have questions, please contact YONSA SUPPORT™ at 1-855-44YONSA (1-855-449-6672)

File

TERMS AND CONDITIONS
Eligible commercially insured patients 18 years or older pay as little as $10/month for a YONSA® prescription. Patients must have a valid prescription and commercial, prescription drug insurance coverage. To enroll in the YONSA® Co-Pay Program (this “Program”), present the Program card along with a valid prescription to the pharmacist at any participating pharmacy.

Terms and Conditions: By enrolling in the Program, you are certifying that you understand these terms and conditions and that you have/will respond truthfully to the questions presented to you for enrollment. Eligibility; The Program is limited to patients residing in the United States, Puerto Rico, Guam, and the Virgin Islands, excluding patients residing in Massachusetts (effective January 1, 2021). If the FDA approves a therapeutically equivalent Rx drug or if an OTC drug containing abiraterone acetate (the active ingredient in YONSA®) becomes available, the Program will exclude patients residing in California. The program is not open to patients with no insurance coverage, who have coverage that imposes no co-pay or co-insurance charge (i.e. insurance covering the full cost of YONSA®), or who are covered by a government program including: Medicare, Medicaid, TRICARE, the Veterans Affairs, the Department of Defense, or have prescription drug coverage under any other federal or state program. In addition, if a patient obtains coverage from such a government program after enrolling in this program, he/she will not be eligible to continue in the Co-Pay Program. Maximum Benefit; The maximum benefit allowed under the Program is $12,000 in each calendar year and no more than $5,000 for each individual prescription filled. Additional Requirements: This offer is not transferrable and cannot be combined with any other offer, free trial, prescription savings card, or discount. Participation in the Program is not conditioned on any past, present, or future purchase. Patients may not apply for reimbursement and for all or any part of any benefit they receive from their health insurance or any third party and must report to their insurer or health plan administrator, if required, that they have enrolled in this program and are/will receive a financial benefit. The Program card is accepted only at participating pharmacies. There may be additional terms and conditions that also apply. Legal Notice: This Program is not health insurance. This Program is void where prohibited or restricted by law. Any sale, purchase, trade, counterfeiting, duplication, or reproduction of this card or offer to do so, is prohibited by law. Term: This offer expires on 3/31/2021 but may be canceled or changed, without notice, at any time. Use of Personal Data: Data related to your redemption of the card may be collected, combined with data from other co-pay card redemptions, de-identified, and shared with the Program sponsor (Sun Pharmaceutical Industries, Inc.), market research, program assessment, and for other lawful purposes.

File

If you have any questions about YONSA SUPPORT™, or would like to enroll, either talk to your doctor or contact us at 1-855-44YONSA
(1-855-449-6672)

IMPORTANT SAFETY INFORMATION Expand

WHAT IS YONSA®?

YONSA® (abiraterone acetate) is a prescription medicine that is used with methylprednisolone to treat prostate cancer that has spread to other parts of the body and no longer responds to medical or surgical treatment that lowers testosterone.

It is not known if YONSA® is safe or effective in children.

IMPORTANT SAFETY INFORMATION

Who should not take YONSA® (abiraterone acetate)?

YONSA® is not for use in women.

Do not take YONSA® if you are pregnant or may become pregnant. YONSA® may harm your unborn baby. Women who are pregnant or may become pregnant should not handle YONSA® tablets without protection, such as gloves.

Before you take YONSA®, tell your healthcare provider about all of your medical conditions, including if you:
  • Have heart problems
  • Have liver problems
  • Have a history of adrenal problems
  • Have a history of pituitary problems
  • Have a partner who is pregnant or may become pregnant
    • Men who are sexually active with a woman who may become pregnant must use effective birth control during treatment and for at least 3 weeks after the final dose of YONSA®.
    • Men who are sexually active with a woman who is pregnant must use a condom.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. YONSA® can interact with many other medicines.

You should not start or stop any medicine before you talk with the healthcare provider who prescribed YONSA®.

If you are taking YONSA®:

  • Take YONSA® and methylprednisolone exactly as your healthcare provider tells you.
  • Take your prescribed dose of YONSA® 1 time a day. Take your prescribed dose of methylprednisolone 2 times a day.
  • YONSA® contains abiraterone acetate. YONSA® and other medications that contain abiraterone acetate may not be the same.
    • Do not switch between YONSA® and other medicines that contain abiraterone acetate unless your healthcare provider tells you to.
    • Follow your healthcare provider’s instructions carefully if you are switching between YONSA® and another medicine that contains abiraterone acetate.
    • Do not take YONSA® and other medicines that contain abiraterone acetate on the same day.
    • If you do not have enough YONSA® to take your full dose or if you have any other questions about YONSA®, talk with your healthcare provider or pharmacist.
  • Your healthcare provider may change your dose of YONSA® if needed.
  • Do not stop taking your prescribed dose of YONSA® or methylprednisolone without talking to your healthcare provider first.
  • Take YONSA® with or without food.
  • Swallow YONSA® tablets whole with water. Do not crush or chew tablets.
  • If you miss a dose of YONSA® or methylprednisolone, take your prescribed dose the following day. If you miss more than 1 daily dose, tell your healthcare provider right away.
  • If you are receiving gonadotropin-releasing hormone (GnRH) therapy, you should continue your therapy during treatment with YONSA and methylprednisolone.
  • If you take too much YONSA®, call your healthcare provider or go to the nearest hospital emergency room right away.
  • Your healthcare provider will do blood tests to check for side effects.

What are the possible side effects of YONSA®?

YONSA® may cause serious side effects, including
  • High blood pressure (hypertension), low blood potassium levels (hypokalemia), and fluid retention (edema). Tell your healthcare provider if you get any of the following symptoms:
    • Dizziness
    • Fast heartbeats
    • Feel faint or lightheaded
    • Headache
    • Confusion
    • Muscle weakness
    • Pain in your legs
    • Swelling in your legs or feet
  • Adrenal problems may happen if you stop taking methylprednisolone, get an infection, or are under stress.
  • Liver problems. You may develop changes in liver function blood tests. Your healthcare provider will do blood tests to check your liver before treatment with YONSA® and during treatment with YONSA®. Liver failure may occur, which can lead to death. Tell your healthcare provider if you notice any of the following changes:
    • Yellowing of the skin or eyes
    • Darkening of the urine
    • Severe nausea or vomiting
The most common side effects of YONSA® include:
  • Weakness
  • Joint swelling or pain
  • Muscle pain
  • Swelling in your legs and feet
  • Hot flushes
  • Diarrhea
  • Vomiting
  • Cough
  • High blood pressure
  • Shortness of breath
  • Trouble sleeping
  • Urinary tract infection
  • Bruising
  • Indigestion
  • Blood in the urine
  • Constipation
  • Upper respiratory tract infection
  • Low red blood cells (anemia)
  • Low blood potassium levels
  • High blood sugars
  • High blood cholesterol and triglycerides
  • Changes in liver function blood tests
  • Certain other abnormal blood tests

YONSA® may affect fertility in males and may affect your ability to father a child. Talk to your healthcare provider if this is a concern for you.

THESE ARE NOT ALL THE POSSIBLE SIDE EFFECTS OF YONSA®.

Talk with your healthcare provider or pharmacist about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088 (1-800-332-1088).

Please see Full Prescribing Information and Patient Information for YONSA® and discuss any questions you have with your doctor.